When you hear weight loss pills, oral products marketed to help reduce body fat. Also known as diet pills, they range from FDA-approved prescriptions to herbal blends sold without oversight. The truth? Most don’t deliver what they promise. But a few—like orlistat, semaglutide, and phentermine—have real science backing them. The problem isn’t that they don’t work. It’s that people expect magic from a pill. Real weight loss still needs diet, movement, and patience. These pills just help remove some of the biggest roadblocks: hunger, cravings, and slow metabolism.
Not all appetite suppressants, drugs that reduce hunger signals to the brain are created equal. Some, like phentermine, are short-term prescriptions for people with obesity. Others, like green tea extract or garcinia cambogia, show up in cheap supplements with zero clinical proof. Then there are fat burners, products claiming to speed up calorie burning. Many contain caffeine, synephrine, or yohimbine—ingredients that might give you a jittery boost but rarely lead to lasting fat loss. And if a product says "clinically proven" but won’t name the study, walk away.
Prescription weight loss drugs, medications approved by health authorities for managing obesity like semaglutide (Wegovy) or liraglutide (Saxenda) work by mimicking gut hormones that tell your brain you’re full. They’re effective—but expensive, and not for everyone. These aren’t quick fixes. They’re tools for people who’ve tried everything else and still struggle. And they come with side effects: nausea, fatigue, even rare cases of pancreatitis. That’s why you need a doctor’s guidance, not a random online pharmacy.
Over-the-counter supplements, non-prescription products sold as dietary aids are a minefield. The FDA doesn’t review them before they hit shelves. That means a bottle labeled "natural weight loss" could contain hidden stimulants, banned substances, or nothing at all. A 2023 study found nearly 1 in 5 weight loss supplements had undeclared pharmaceuticals—like sibutramine, pulled from the market for causing heart attacks. You’re not just wasting money. You’re risking your health.
What’s missing from most ads? Real results. People who lose weight with these pills usually do it because they changed how they ate and moved. The pill just made it easier. That’s why the best outcomes come from combining medication with behavior change—not replacing it.
Below, you’ll find real reviews, comparisons, and warnings about what’s actually out there. No fluff. No hype. Just what works, what doesn’t, and what you need to know before you buy another bottle.
A side‑by‑side look at Alli (Orlistat) versus other weight‑loss pills, covering how they work, costs, benefits, side effects, and how to pick the right option for you.