Nitroglycerin is a fast-acting medicine most people use for chest pain (angina). It opens blood vessels so the heart gets more oxygen and works less hard. If you or someone you care for gets sudden chest tightness, knowing the basics about nitroglycerin can make a real difference.
Nitroglycerin turns into nitric oxide in the body, which relaxes smooth muscle in blood vessel walls. That lowers the pressure the heart pumps against and eases chest pain. You’ll see nitroglycerin in a few forms: sublingual tablets or spray for quick relief, transdermal patches for longer control, ointment for slow absorption, and IV forms used in hospitals. Brand names include Nitrostat (sublingual) and Nitro-Dur (patch).
If you have sublingual tablets or spray, sit down first. Place the tablet under your tongue or spray into your mouth, don’t swallow it. If pain continues, you can take another dose after 5 minutes. Do not take more than three doses in 15 minutes. If chest pain lasts after three doses, call emergency services — this can be a heart attack.
For patches, apply to a clean, dry area on the chest or upper arm. Follow the schedule your doctor gives; many people remove the patch at night to reduce tolerance. Ointment should be measured carefully with the applicator provided. Never cut a patch unless the instructions say to. Always store tablets in their original container because light and humidity can make them weaker.
Tell your doctor about other medicines you take. Never use nitroglycerin with sildenafil (Viagra), tadalafil (Cialis), or similar drugs for erectile dysfunction — the two together can cause dangerous drops in blood pressure. Also mention blood pressure meds, certain antidepressants, and any heart rhythm drugs.
Watch blood pressure and how you feel when you stand up. Nitroglycerin commonly causes headaches, dizziness, flushing, or low blood pressure. These often ease after a few doses, but if you feel faint or very lightheaded, lie down and raise your legs and call for help if needed.
Pregnant or breastfeeding? Tell your clinician — nitroglycerin may be used but needs a healthcare check first. If you notice severe side effects like fainting, irregular heartbeat, severe headache that won’t ease, or signs of allergic reaction (rash, swelling, trouble breathing), get medical help right away.
Keep nitroglycerin away from heat and moisture, check expiry dates, and replace old medicine. If you’re unsure how to use a spray, patch, or ointment, ask your pharmacist to show you. A small bit of practice and knowing when to call for help will keep you safer if chest pain strikes.
Nitroglycerin has had a profound impact on global health and wellbeing, mainly through its use in treating heart conditions. It's a game-changer in managing angina and heart failures, providing sufferers relief and improving their quality of life. However, like all medications, nitroglycerin also has potential side effects that need to be considered. Overall, its role in cardiovascular health has been instrumental, making a significant difference in the lives of millions worldwide. Yet, it's essential to remember that each patient's response may vary, and it's always crucial to use it under medical supervision.